Dossier to IUCLID upload functionality

The Dossier to IUCLID upload functionality aims to assist applicants to upload existing structured information and attachments to IUCLID in an efficient manner:

It covers the creation of literature reference entities for GLP study reports, including PDF attachments and metadata, based on dossier information. However, this type of upload is constrained, as it can only use the information provided in the metamodel of the builder, which is not sufficient to support other IUCLID entities next to literature references.

For this reason, this type of upload to IUCLID cannot be further extended. For other types of uploads, like from existing tabular data in Excel or CSV-format to specific & complex IUCLID documents please see the IUCLID Integration Platform.

Creation of literature references based on dossiers

Below you can see a screenshot of the literature reference upload functionality, being part of the eSubmission builder tool:

  • The middle pane shows the ToC of the dossier version from which you can select nodes to be uploaded to IUCLID
  • The right pane shows the upload jobs and their synchronisation status icon
  • The lower right pane shows individual jobs details, including a link to the IUCLID literature reference, once uploaded


The tool requires the connection to an on-premise IUCLID installation. Unfortunately, ECHA does not support the synchronisation for ECHA cloud instances via the IUCLID interface.


The Dossier to IUCLID upload functionality, which is part of the eSubmission builder release 1.1.0, covers the creation of literature references from selected ToC nodes in a dossier.

You can download the latest version of the eSubmission builder here

Outlook: Upload of existing tabular data

The eSEG is discussing to extend the scope of the IUCLID entities that can be partially filled from existing tabular data in Excel/CSV format in a specific format. This functionality will be a separate download and not be bundled with the eSubmission builder.

Please check this page for updates or contact the technical support for more information.